Press Releases

Product demonstrations and educational presentations underscore the company’s leadership in advancing care for patients with benign prostatic hyperplasia (BPH)

Teleflex Announces the Launch of the UroLift^® System in Japan for the Treatment of Benign Prostatic Hyperplasia (BPH)

Initial Cases Have Now Been Performed in Japan

Will expand patient access to breakthrough BPH treatment

WAYNE, Pa.--October 29, 2021--Teleflex Incorporated (NYSE: TFX) announced today that the UroLift^® System was honored by DTC Perspectives with a Bronze Award in the “Best New Branded Television Campaign” category and an Honorable Mention in the “Best Branded Website” category. The National Advertising Awards were announced at the Annual DTC National Conference in Boston, which was held October 12-14.

The campaign, “Theater ‘Flow’,” is the first national TV campaign in Teleflex history. The ad features prominent imagery associated with symptoms of enlarged prostate, or benign prostatic hyperplasia (BPH), including increased frequency, a weak urine stream and feeling of incomplete emptying of the bladder. The ad includes a clear call to action to visit the branded website and to call a toll-free number. The UroLift System is a minimally invasive treatment for lower urinary tract symptoms due to BPH, a condition that leads more than 12 million men in the U.S. to seek treatment every year.¹

“Many big pharma companies with large advertising budgets were selected as finalists for the Best New Branded Television Campaign,” said Bryan Holmes, Global Vice President, Marketing and Business Development of the Teleflex Interventional Urology Business Unit. “We were somewhat of an underdog from this perspective but were able to create a terrific campaign that stood out to the judges. We are proud of our skilled team, and our success was a result of their hard work and dedication to producing quality work that spoke to our target audience.”

“DTC works when potential customers ask their doctor about the advertised product. DTC works really well when there is a large pool of potential users who are informed about something new to help them. The UroLift System meets both criteria. The pool of men with BPH is large, and UroLift is a novel approach,” said Bob Ehrlich, Chairman, DTC Perspectives, Inc.

The campaign aired for 25 weeks, from July 6 to December 30, 2020. Over the course of the campaign 3,108 television ads in :60 and :30 second spots ran on national cable stations. The response to the television ad was nearly double what was originally planned, demonstrating a significant breakthrough to the brand’s target market. Additionally, traffic to the branded website increased 146%.

The campaign was developed in partnership with the award-winning creative director Rocky Botts of the Rocky Botts Creative agency.

About the DTC Perspectives Awards
DTC Perspectives, the leading forum for direct-to-consumer (DTC) advertising thought leaders, honors a dynamic group of pharmaceutical companies and brands at the much-anticipated DTC National Advertising Awards. Learn more about the awards at DTC Perspectives.

About the UroLift^® System
The UroLift System is a minimally invasive treatment for lower urinary tract symptoms due to benign prostatic hyperplasia (BPH). It is indicated for the treatment of symptoms of an enlarged prostate up to 100 cc in men 45 years or older (50 years outside U.S.). The UroLift^® permanent implants, delivered during an outpatient procedure, relieve prostate obstruction, without heating, cutting, destruction of or removing prostate tissue. The UroLift^® System can be used to treat a broad spectrum of anatomies, including obstructive median lobe.² It is the only leading BPH procedure shown to not cause new onset, sustained erectile or ejaculatory dysfunction.^*3-5 Most common adverse events are temporary and can include hematuria, dysuria, micturition urgency, pelvic pain, and urge incontinence.³ Rare side effects, including bleeding and infection, may lead to a serious outcome and may require intervention. Individual results may vary. The prostatic urethral lift procedure (using the UroLift^® System) is recommended for the treatment of BPH in both the American Urological Association and European Association of Urology clinical guidelines. More than 300,000 men have been treated with the UroLift^® System in select markets worldwide.^† Learn more at UroLift.com. Rx only.

About Teleflex Interventional Urology
The Teleflex Interventional Urology Business Unit is dedicated to developing innovative, minimally invasive, and clinically effective devices that address unmet needs in the field of urology. Our focus is on improving the standard of care for patients with BPH using the UroLift^® System, a minimally invasive, permanent implant system that treats symptoms while preserving sexual function.^*3-5 Learn more at NeoTract.com.

About Teleflex Incorporated
Teleflex is a global provider of medical technologies designed to improve the health and quality of people’s lives. We apply purpose-driven innovation — a relentless pursuit of identifying unmet clinical needs — to benefit patients and healthcare providers. Our portfolio is diverse, with solutions in the fields of vascular and interventional access, surgical, anesthesia, cardiac care, urology, emergency medicine, and respiratory care. Teleflex employees worldwide are united in the understanding that what we do every day makes a difference. For more information, please visit Teleflex.com.

Teleflex is the home of Arrow^®, Deknatel^®, LMA^®, Pilling^®, Rusch^®, UroLift^®, and Weck^® — trusted brands united by a common sense of purpose.

Contacts:
For Teleflex Incorporated:
Lawrence Keusch
Vice President, Investor Relations and Strategy Development

John Hsu, CFA
Vice President, Investor Relations
investors.teleflex.com
610.948.2836

Media:
Nicole Osmer
nicole@healthandcommerce.com
650.454.0504

*No instances of new, sustained erectile or ejaculatory dysfunction in the L.I.F.T. pivotal study.
† Management estimate based on product sales and average units per procedure.

References
1. NeoTract US Market Model estimates for 2020, data on file
2. Rukstalis, Prostate Cancer and Prostatic Dis 2018
3. Roehrborn, J Urology 2013 L.I.F.T. Study
4. AUA BPH Guidelines 2003, 2020
5. McVary, J Sex Med 2016

Teleflex, the Teleflex logo, NeoTract, the NeoTract logo and UroLift are trademarks or registered trademarks of Teleflex Incorporated or its affiliates, in the U.S. and/or other countries.

Late-Breaking Data Presentation Reveals How UroLift PUL’s Post-Operative Events Compare With Other Minimally Invasive Procedures and Traditional Surgery for the Treatment of BPH

New real-world data findings along with new product evolutions demonstrate why the UroLift® System is the right solution for most BPH patients

WAYNE, PA. – September 9, 2021 – Teleflex Incorporated (NYSE: TFX) today announced that two new UroLift System products, the UroLift Advanced Tissue Control (ATC) System and the UroLift 2 System, will be launched at the American Urological Association (AUA) 2021 Annual Meeting taking place virtually September 10–13. New emerging data from the largest analysis of U.S. healthcare claims within the field of benign prostatic hyperplasia (BPH) comparing complication rates (defined as a post-operative procedure performed during a return visit to an outpatient setting) and surgical retreatment rates of BPH procedures, including the UroLift System, will also be presented.

WAYNE, Pa., August 20, 2021 (GLOBE NEWSWIRE) -- Teleflex Incorporated (NYSE: TFX) today announced the publication of clinical data for the UroLift^® System in the peer-reviewed journal Prostate Cancer and Prostatic Disease. This study explains the mechanism of action through which the UroLift System provides long-term durability and sustained results for patients with benign prostatic hyperplasia (BPH), also referred to as enlarged prostate.

The UroLift System implants provide rapid relief from disruptive lower urinary tract symptoms (LUTS) through a minimally invasive procedure that pulls back enlarged prostate tissue. This published study is unique in its amalgamation of three different facets of research by including pre-clinical canine tissue, human tissue, and post-market surveillance data. Tissue samples were examined from twenty-four healthy canines and four human patients who were implanted with the UroLift System. Researchers reviewed the microscopic structure on all tissue samples to uncover any potential changes attributed to the implants.

The microscopic evaluation found that the extracted tissues revealed normal-appearing tissue with minimal-mild inflammation and no encrustation, indicating a stable and normal healing response. The data support a long-term biological mechanism of action whereby compression-induced localized tissue remodeling is initiated by the UroLift System implant placement and leads to a widened prostatic urethra. Furthermore, post-market surveillance data of over 770,000 UroLift System devices support that the implant is stable and remains fixed after proper deployment, and demonstrate low rates of breakage (0.004%) and encrustation (0.006%). Taken together, the biocompatibility and stability of the UroLift System implants appear to be superior to prostatic stents, with studies of prostatic stents showing that up to 47% of men require removal of their implants due to complications associated with migrations and encrustations.¹

The UroLift implant pulls the enlarged prostate toward the capsule, thereby mechanically creating an immediate, visible deobstruction in the prostatic urethra. The researchers discuss this “prostate lift” is a fundamentally distinct mode of action compared with not only prostatic stents, but also thermal ablation techniques that induce tissue damage and may result in extended periods of edema, retention/catheterization, and higher risks of urinary infections and ejaculatory dysfunction. ^2,3,4,5,6,7

“The UroLift System is the first mechanical prostatic implant to demonstrate safe and effective treatment of BPH without common issues associated with prior stents. This study describes in detail the unique prostate lift mechanism of action that is the basis of its durable outcomes,” said Dr. Peter Chin, Clinical Associate Professor, Graduate School of Medicine, University of Wollongong, and author on the paper. “Not only are the results seen with the UroLift System sustainable, but the implants can provide a superior patient experience during the early recovery period⁴, and rapid symptom relief and preservation of sexual function*”⁹

“More than 12 million men in the U.S. are treated for BPH/LUTS. With over 250,000 patients treated globally with the UroLift System, it has been the right solution for many patients,” said Jacqueline Welch, Medical Director of the Teleflex Interventional Urology business unit. “Physicians can implant the UroLift System with confidence due to the demonstrated long-term durability and sustained BPH relief that it provides.”¹⁰

About the UroLift^® System
The UroLift^® System is a minimally invasive treatment for lower urinary tract symptoms due to benign prostatic hyperplasia (BPH). It is indicated for the treatment of symptoms of an enlarged prostate up to 100cc in men 45 years or older. The UroLift permanent implants, delivered during an outpatient procedure, relieve prostate obstruction without heating, cutting, destruction or removing prostate tissue. The UroLift System is the only leading BPH procedure shown to not cause new onset, sustained erectile or ejaculatory dysfunction.^{* 9,10,11,12} Most common adverse events are temporary and can include hematuria, dysuria, micturition urgency, pelvic pain, and urge incontinence.⁹ Rare side effects, including bleeding and infection, may lead to a serious outcome and may require intervention. Individual results may vary. The Prostatic Urethral Lift procedure (using the UroLift System) is recommended for the treatment of BPH in both the American Urological Association and European Association of Urology clinical guidelines. More than 250,000 men have been treated with the UroLift System in select markets worldwide.^† Learn more at www.UroLift.com.

About Teleflex Interventional Urology
The Teleflex Interventional Urology Business Unit is dedicated to developing innovative, minimally invasive and clinically effective devices that address unmet needs in the field of urology. Our focus is on improving the standard of care for patients with BPH using the UroLift System, a minimally invasive permanent implant system that treats symptoms while preserving sexual function.^*9-11 Learn more at NeoTract.com.

About Teleflex Incorporated
Teleflex is a global provider of medical technologies designed to improve the health and quality of people’s lives. We apply purpose driven innovation – a relentless pursuit of identifying unmet clinical needs – to benefit patients and healthcare providers. Our portfolio is diverse, with solutions in the fields of vascular and interventional access, surgical, anesthesia, cardiac care, urology, emergency medicine and respiratory care. Teleflex employees worldwide are united in the understanding that what we do every day makes a difference. For more information, please visit Teleflex.com.

Teleflex is the home of Arrow^®, Deknatel^®, LMA^®, Pilling^®, Rusch^®, UroLift^® and Weck^® – trusted brands united by a common sense of purpose.

+Dr. Chin was an investigator for the PUL feasibility clinical trial and the LIFT pivotal study. He is also a paid consultant for NeoTract Inc./Teleflex.

Real-World Claims Data Presented at Annual European Association of Urology Congress Reveal Overall Complication Rates are Lowest after Treatment with the UroLift System

Presentations to Provide New Insights on the Real-World Effectiveness and Durability of Leading Minimally Invasive Procedure for Enlarged Prostate

Teleflex survey finds “extreme bathroom planning” to accommodate urinary symptoms common with an enlarged prostate (BPH) impacts daily activities